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Doxylamine
Clinical data
Trade namesUnisom, Vicks Formula 44 (in combination with Dextromethorphan), others
AHFS/Drugs.comMonograph
MedlinePlusa682537
Pregnancy categoryAU: A US: B (No risk in non-human studies) A (Briggs)
Routes of administrationBy mouth
ATC codeR06AA09 ( WHO )
Legal status
Legal statusAU: S3 (Pharmacist only) US: OTC
Pharmacokinetic data
BioavailabilityOral: 24.7% [2] Intranasal: 70.8% [2]
MetabolismHepatic (CYP2D6, CYP1A2, CYP2C9) [1]
Elimination half-life10–12 hours [1]
ExcretionUrine (60%), feces (40%) [3]

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  • Unisom all alternative names: decapryn, donormyl, dormidina, dossilamina, doxilamina, doxilamine, doxilmina, doxilminio, doxinate, doxylamin, doxylaminum, dozile, gittalun, histadoxylamine, hoggar, lidene, mereprine, nocpaz, restavit, restwel, sanalepsin, sedaplus, somnia, sulamine, valocordin, vistaril12, zarcop, zyrtec4
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