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This medication is best taken by mouth on an empty stomach, at least 1 hour before or 2 hours after a meal, usually 1 or 2 times daily or as directed by your doctor. Take this medication with a full glass of water (8 ounces/240 milliliters) unless directed otherwise. Vibramycin (doxycycline) pkg. 100 mg 120 amount of packaging.

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Clinical data
Pronunciation/ ˌ d ɒ k s ɪ ˈ s aɪ k l iː n / DOKS -i- SY -kleen
Trade namesDoryx, Doxyhexal, Doxylin among others
License dataUS   FDA: Doxycycline
Pregnancy categoryAU: D US: D (Evidence of risk)
Routes of administrationBy mouth, IV [1]
ATC codeJ01AA02 ( WHO ) A01AB22 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Protein binding90%
Elimination half-life15–25 hours
ExcretionUrine (40%)

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All tetracyclines form a stable calcium complex in any bone-forming tissue.see section 4.

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